Current Studies

Randomized Controlled Trials

The Harmonized Interventions to Maintain health via Appropriate risk factor modification and Lifestyle changes in Adolescent and Young Adult cancer Survivors (HIMALAYAS) trial 

  • Nominated Principal Investigator: Thavendiranathan, D.
  • Co-Principal Investigators: Abdel-Qadir, H., Adams, S.C., Awadalla, P., Charpentier, D., Davis, M., Gyenes, G., Goddard, K., Gupta, A., Hayami, D., Hodgson, D., Lau, B., Oh, P., Paterson, I., Pituskin, E., & Tournoux, F.
  • Co-Investigators: Brezden-Masley, C., Cifra, B., Cooks, B., Dore, I., Gauvin, L., Grandy, S., Ivers, N., Kirkham, A., Lega, I., McKillop, S., Mulvagh, S., Nadler, M., Nathan, P., Price, J., Rac, V.,  Rayson, D., Ribeiro, P., Sabiston, C.M., Samouelian, V., Santa Mina, D., Spavor, M., Thorpe, K. & Tomlinson, G.
  • Fellows & Trainees: Bonsignore, A., Brahmbhatt, P., Calvillo-Arguelles, Lee, L. & Rivera Theurel, F.
  • Design: Multi-centre randomized controlled trial
  • Funding: Canadian Cancer Society; Canadian Institutes of Health Research
  • Status: REB review

The Harmonized Interventions to Maintain health via Appropriate risk factor modification and Lifestyle changes in Adolescent and Young Adult cancer Survivors (HIMALAYAS) pilot study 

  • Principal Investigators: Thavendiranathan, D., Hodgson, D., Oh, P., Abdel-Qadir, H. & Adams, S.C. 
  • Co-Investigators: Gupta, A., Nathan, P., Awadalla, P., Santa Mina, D., Sabiston, C.M., Brezden-Masley, C., Cifra, B., Lega, I., Price, J., Ross, H., Cafazzo, J., Duhamel, J., Woo, A., Rac, V. & Ivers, N. 
  • Design: Randomized controlled feasibility trial
  • Funding: Peter Munk Cardiac Centre Innovation Fund; MSH-UHN AMO Innovation Fund
  • Status: REB review

Examining the Psychosocial and Physiological Impact of an Interventional Yoga Program on Young Adult Cancer Patients on Treatment

  • Investigators: Tam, S., MacMillan, M., Lega, I., Gupta, A., Adams, S.C. (Co-PI) & Smith-Turchyn, J. (Co-PI
  • Design: Randomized controlled trial
  • Funding: N/A
  • Status: REB review

The Prehabilitation to Improve Cancer Surgery Outcomes in newly diagnosed adolescent and young adult Extremity Sarcoma patients (PICaSO-ES) trial

  • Investigators: Adams, S.C. (Co-PI), Chen, M., Gupta, A., Wunder, J., Ferguson, P., D’Agostino, N., Mitchell, L., Sabiston, C.M., Griffin, A., Govindarajan, A. & Santa Mina, D. (Co-PI)
  • Design: Randomized controlled feasibility trial
  • Funding: Michael Kamin Heart Award in AYA Oncology / Princess Margaret AYA Oncology Program
  • Status: On hold due to COVID-19

Prospective Cohort Trial

The Rural Exercise for Cancer Patients and Survivors (RECaPS) project

  • Investigators: Adams, S.C. (Research Lead), Smith-Turchyn, J., Dempster, H., Trenholm, R., Lavigne, D., Allen, L., Hailstone, K., Sabiston, C.M., Santa Mina, D. & MacMillan, L. (PI)
  • Design: Single arm feasibility cohort study
  • Funding: Northern Ontario Academic Medical Association / Northern Ontario School of Medicine
  • Status: On hold due to COVID-19

Cross-Sectional Survey Studies

The Exercise Oncology Knowledge Mobilization Initiative (ExOnc-KMI): Defining the path to implementation

  • Investigators: Adams, S.C., Smith-Turchyn, J., Santa Mina, D., Neil-Sztramko, S., Cormie, P., Culos-Reed, N., Campbell, K., Pugh, G., Dore, I., Nadler, M., Langelier, D., Phipps, D., Schmitz, K. & Sabiston, C.M. (PI)
  • Design: International modified Delphi survey study
  • Funding: Canadian Breast Cancer Foundation / Canadian Cancer Society Research Institute
  • Status: Completed

Assessing exercise and physical activity support needs of cancer patients and survivors living in rural communities. (A sub-study of The RECaPS Project).

  • Investigators: Smith-Turchyn, J. (Research Lead), Adams, S.C., Dempster, H., Trenholm, R., Lavigne, D., Allen, L., Hailstone, K., Sabiston, C.M., Santa Mina, D. & MacMillan, L. (PI)
  • Design: Survey-based needs assessment
  • Funding: Northern Ontario Academic Medical Association / Northern Ontario School of Medicine
  • Status: Completed

Select Publications

Citation: Scott JM, Adams SC, Koelwyn GJ, Jones LW. Cardiovascular late effects and exercise treatment in breast cancer: Current evidence and future directions. Can J Cardiol. 2016;32(7):881-890.

Citation: Adams SC, DeLorey DS, Davenport MH, et al. Effects of high-intensity aerobic interval training on cardiovascular disease risk in testicular cancer survivors: A phase 2 randomized controlled trial. Cancer. 2017;123(20):4057-4065.

Citation: Adams SC, DeLorey DS, Davenport MH, Fairey AS, North S, Courneya KS. Effects of high-intensity interval training on fatigue and quality of life in testicular cancer survivors. Br J Cancer. 2018;118(10):1313-1321.

Citation: Scott JM, Li N, Liu Q, et al. Association of exercise with mortality in adult survivors of childhood cancer. JAMA Oncol. 2018;4(10):1352-1358.

Citation: Scott JM, Zabor EC, Schwitzer E, et al. Efficacy of exercise therapy on cardiorespiratory fitness in patients with cancer: A systematic review and meta-analysis. J Clin Oncol. 2018;36(22):2297-2305.

Citation: Adams SC, Segal RJ, McKenzie DC, et al. Impact of resistance and aerobic exercise on sarcopenia and dynapenia in breast cancer patients receiving adjuvant chemotherapy: a multicenter randomized controlled trial. Breast Cancer Res Treat. 2016;158(3):497-507.

Citation: Adams SC, Schondorf R, Benoit J, Kilgour RD. Impact of cancer and chemotherapy on autonomic nervous system function and cardiovascular reactivity in young adults with cancer: a case-controlled feasibility study. BMC Cancer. 2015;15(414):414.

Citation: Mina DS, Langelier D, Adams SC, et al. Exercise as part of routine cancer care. The Lancet Oncology. 2018;19(9):e433-e436.